Focused Ultrasound Therapy

Early Stage square

Focused ultrasound is an early-stage, noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with coarctation of the aorta. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the body without damaging surrounding normal tissue. Where the beams converge, the ultrasound produces precise ablation (thermal destruction of tissue) enabling the narrowed portion (the coarctation) to be ablated and enable better flow of the blood passed the lesion. While early results are promising, there is still much to be done before this technology will be widely available.

The primary options for treatment of coarctation of the aorta include medication and invasive surgery.

For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications and lower cost.

Advantages:

  • Focused ultrasound is noninvasive, so it does not carry added concerns like surgical wound healing or infection.
  • Focused ultrasound can reach the desired target without damaging surrounding tissue.
  • It can be repeated, if necessary.

Clinical Trials

At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment for coarctation of the aorta.

Regulatory Approval and Reimbursement

Focused ultrasound treatment for coarctation of the aorta is not yet approved by regulatory bodies or covered by medical insurance companies.

Notable Papers

Development of an ex vivo porcine model of coarctation of the aorta: Possible treatment applications with MR-guided HIFU using boiling histotripsy. Presentation by Sergio Vegas Salas. 

See additional references from PubMed.

 

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