Focused Ultrasound Therapy
Focused ultrasound is an early-stage, noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with osteomyelitis. This novel technology focuses beams of ultrasound energy precisely and accurately on targets in the body without damaging surrounding normal tissue. Where the beams converge, the ultrasound can produce local hyperthermia of the infected tissue that enables better penetration of the antibiotics, and enables osteomyelitis to be treated more effectively. While some work has been accomplished, there is still much to be done before this technology will be widely available.
The primary options for treatment of osteomyelitis include medication, invasive surgery and sometimes amputation.
For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications, improved outcomes and lower cost.
- Focused ultrasound is noninvasive, so it does not carry added concerns like surgical wound healing or infection.
- Focused ultrasound can reach the desired target without damaging surrounding tissue.
- It can be repeated, if necessary.
At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment of osteomyelitis.
Regulatory Approval and Reimbursement
Focused ultrasound treatment for osteomyelitis is not yet approved by regulatory bodies or covered by medical insurance companies.
Beserra A, Pichardo S, Kisselgoff D, Peeva V, Curiel L. Targeting feasibility evaluation of magnetic resonance-guided focused ultrasound in the management of osteomyelitis: a virtual treatment planning study in 75 patients. Int J Hyperthermia. 2019;36(1):1012-1023. doi: 10.1080/02656736.2019.1663944.
Evaluation of Magnetic Resonance Guided Focused Ultrasound in the Management of Osteomyelitis: Targeting Feasibility. Presentation by Amanda Beserra. 2018.
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