Focused Ultrasound Therapy

Early Stage square

Focused ultrasound is an early-stage, noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with a ureterocele. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the body without damaging surrounding normal tissue. Where the beams converge, the ultrasound produces cavitation (histotripsy) to achieve tissue fractionation (punctures) in a tissue model of a ureterocele wall. More research is needed to establish the safety and efficacy of this procedure before proceeding to clinical trials.

The primary options for treatment of a ureterocele include medication and invasive surgery.

For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications and lower cost.

Advantages:

  • Focused ultrasound is noninvasive, so it does not carry added concerns like surgical wound healing or infection.
  • Focused ultrasound can reach the desired target without damaging surrounding tissue.
  • It can be repeated, if necessary.

Clinical Trials

At the present time, there are no clinical trials recruiting patients for treatment of ureterocele.

Regulatory Approval and Reimbursement

Focused ultrasound treatment for ureterocele is not yet approved by regulatory bodies or covered by medical insurance companies.

Notable Papers

Maxwell AD, Hsi RS, Bailey MR, Casale P, Lendvay TS. Noninvasive ureterocele puncture using pulsed focused ultrasound: an in vitro study. J Endourol. 2014 Mar;28(3):342-6.

Click here for additional references from PubMed.

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