Foundation Funded Research Projects

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Showing 100 out of 133 research projects
Category Project Name (Click on the project name for more info) Primary Research Site Principal Investigator Funding Dates Program
Brain tumors, Glioblastoma Focused ultrasound immunomodulation for pancreatic cancer
      Mar 12, 2019 - Mar 12, 2020 Immunotherapy
      Brain, General Microbubble enhanced FUS treatments in the brain: impact of bubble distribution...
        Mar 01, 2019 - Mar 01, 2020 Brain Program
        Convective skin-cooling device for use with existing MRgFUS systems to prevent...
          Feb 28, 2019 - Nov 01, 2019 Research Award
          Microbubble distribution in the brain: a real-time intra-operative map to...
            Feb 21, 2019 - Feb 21, 2020 Brain Program
            Parkinson’s Disease MRGFUS GENE DELIVERY FOR NEUROPROTECTION IN PARKINSON'S DISEASE
                Jan 18, 2019 - Jan 18, 2020 Brain Program
                Development of a turnkey USgFUS preclinical research platform
                  Jan 04, 2019 - Jan 03, 2020 Research Award
                  Massively Parallel Nonlinear Ultrasound Simulation of Histotripsy in the Brain
                    Jan 01, 2019 - Nov 30, 2022 Brain Program
                    Drug delivery strategies using drug-loaded extracellular vesicles generated by...
                      Dec 11, 2018 - Dec 10, 2019 Research Award
                      Movement Disorders, General Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy for Tremor...
                        Sep 28, 2018 - Sep 27, 2019 Research Award
                        Non-invasive varicose vein treatment by HIFU under ultrasound guidance: Phase...
                          Sep 13, 2018 - Sep 12, 2019 Research Award
                          Liver tumors Non-invasive Focused Ultrasound Ablation for the Treatment of...
                            Sep 13, 2018 - Sep 12, 2019 Research Award
                            Brain tumors, General Safety study: sonodynamic therapy with 5-ALA in a porcine model
                              Jun 05, 2018 - Jun 05, 2019 Brain Program
                              Psychiatric disorders Phase I trial of MR-guided Focused Ultrasound (MRgFUS) bilateral capsulotomy...
                                Jun 05, 2018 - Jun 04, 2020 Brain Program
                                Epilepsy Focused ultrasound thalamotomy for the prevention of secondary generalization...
                                  Jun 01, 2018 - May 31, 2018 Brain Program
                                  Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (9L Line)
                                    Apr 24, 2018 - Apr 24, 2019 Brain Program
                                    Brain tumors, General Microvascular Ablation of Intracranial Gliomas with Focused Ultrasound (F98...
                                        Apr 06, 2018 - Apr 06, 2019 Brain Program
                                        Stroke, Thromboembolic Selective opening of the blood brain barrier using focused ultrasound combined...
                                          Apr 04, 2018 - Apr 04, 2019 Brain Program
                                          Brain, General Sonodynamic therapy for treatment of C6 glioma in a rat model proof-of-concept...
                                            Apr 04, 2018 - Oct 04, 2018 Brain Program
                                            Brain, General Focused ultrasound for treatment of deep-seated cerebral cavernous malformations
                                              Mar 26, 2018 - Mar 26, 2019 Brain Program
                                              Soft tissue tumors Investigation of the immunostimulatory response to high intensity focused...
                                                Mar 12, 2018 - Mar 12, 2019 Veterinary
                                                Back & neck pain Focused ultrasound mediated neuromodulation for the treatment of spinal cord...
                                                  Mar 05, 2018 - Mar 05, 2019 Brain Program
                                                  Investigation of focused ultrasound mediated enhancement of chronic non-...
                                                    Feb 12, 2018 - Feb 12, 2019 Veterinary
                                                    General, Technology Laser-generated Focused Ultrasound Transducer for Transcranial Applications
                                                      Feb 08, 2018 - Apr 22, 2019 Brain Program
                                                      General, Technology Use of shock-wave exposures for accelerating thermal ablation of targeted...
                                                        Feb 07, 2018 - Apr 06, 2019 Research Award
                                                        Bladder tumors Focused Ultrasound Mediated Drug Delivery across the Urothelium
                                                          Feb 06, 2018 - Feb 05, 2019 Research Award
                                                          Pancreatic tumors Focused Ultrasound Driven Drug Release From Theranostic Nanoparticles For The...
                                                            Jan 24, 2018 - Jan 24, 2019 Research Award
                                                            Accessibility and Benefit of FUS treatment for inoperable Lung Cancer Patients,...
                                                              Dec 14, 2017 - Feb 13, 2019 Research Award
                                                              Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                                                Nov 30, 2017 - Mar 30, 2018 Research Award
                                                                Acoustic Backscatter-based 3D Mapping of Cavitation and Skull Surface in...
                                                                  Oct 31, 2017 - Dec 31, 2018 Research Award
                                                                  Back & neck pain Safety and initial feasibility of using the Neurolyser XR device for the...
                                                                    Sep 26, 2017 - Mar 25, 2019 Research Award
                                                                    Parkinson’s Disease MRgFUS Blood-Brain Barrier Drug Delivery with AAV2 Gene Therapy Microbubble...
                                                                      Sep 01, 2017 - Aug 31, 2018 Research Award
                                                                      Safety and Effectiveness of Sacroiliac Joint Palliation in Swine using MRgFUS
                                                                        Jul 01, 2017 - Jun 30, 2018 Research Award
                                                                        Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                          May 17, 2017 - Nov 17, 2017 Brain Program
                                                                          Brain tumors, Metastasis Focused Ultrasound to Enhance Immunotherapy for Metastatic Brain Melanoma
                                                                            May 05, 2017 - Sep 04, 2018 Brain Program
                                                                            Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                              May 01, 2017 - Nov 01, 2017 Brain Program
                                                                              Patterning of bone regeneration via ultrasound activation of heat shock-...
                                                                                Mar 01, 2017 - Feb 28, 2018 Research Award
                                                                                Brain tumors, General A Feasibility Safety Study Using the ExAblate 4000 system in Management of...
                                                                                  Feb 27, 2017 - Feb 26, 2019 Brain Program
                                                                                  Acoustic Parameters of Bone as a function of HU and MRI
                                                                                    Feb 20, 2017 - Feb 21, 2018 Brain Program
                                                                                    Alzheimer’s Disease A Study to Evaluate the Safety and Feasibility of Blood-Brain Barrier (BBB)...
                                                                                      Jan 12, 2017 - Jan 11, 2019 Brain Program
                                                                                      Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                        Nov 29, 2016 - May 19, 2017 Brain Program
                                                                                        Real-time Treatment Monitoring by Diffusion MRI
                                                                                          Nov 29, 2016 - Nov 28, 2017 Brain Program
                                                                                          Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                            Nov 07, 2016 Brain Program
                                                                                            Brain, General FUS-mediated Neuromodulation from Unanesthetized Freely-moving Animals
                                                                                              Oct 01, 2016 - Sep 30, 2017 Research Award
                                                                                              Pancreatic tumors Defining Basic Properties of Physical Immunotherapy using HIFU and Immune...
                                                                                                Sep 07, 2016 - Jun 07, 2019 Immunotherapy
                                                                                                Brain tumors, Glioblastoma Focused Ultrasound Immunomodulation in a Mouse GL261 Intracranial Glioma
                                                                                                  Aug 15, 2016 - Feb 15, 2017 Brain Program
                                                                                                  Parkinson’s Disease Antibody Delivery Through the BBB Opening in an Alpha-Synuclein Model
                                                                                                    Aug 15, 2016 - Oct 15, 2017 Brain Program
                                                                                                    Liver tumors A novel genetic reprogramming therapy for hepatocellular carcinoma using...
                                                                                                      Jul 01, 2016 - Jun 30, 2017 Veterinary
                                                                                                      Brain tumors, Glioblastoma Ultrasound-mediated delivery of siRNA for enhancing temozolomide efficacy...
                                                                                                        Jun 01, 2016 - Dec 15, 2017 Research Award
                                                                                                        Parkinson’s Disease Minimally-Invasive Therapy for Parkinson’s Disease Achieved by the Focused U...
                                                                                                          Feb 04, 2016 - Feb 03, 2017 Brain Program
                                                                                                          Brain, General Development and Calibration of MR Techniques for In-Vivo Bone Thermometry
                                                                                                            Feb 01, 2016 - Aug 16, 2018 Brain Program
                                                                                                            Alzheimer’s Disease Effects of FUS on CNS Uptake and Efficacy of an Anti-Amyloid Antibody in Aged...
                                                                                                              Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                                              General, Cancer Ultrasound ablation combined with immunotherapy: priming to enhance efficacy
                                                                                                                Feb 01, 2016 - Jan 31, 2017 Brain Program
                                                                                                                Brain, General Neuro Focused Ultrasound MR Coil Fabrication and Testing
                                                                                                                  Jan 06, 2016 - Apr 06, 2018 Brain Program
                                                                                                                  Kidney tumors Evaluation of the Systemic Response to Boiling Histotripsy Treatment for Renal...
                                                                                                                    Dec 01, 2015 - Apr 30, 2017 Research Award
                                                                                                                    Brain tumors, General A Chronic Pig Study of Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                                                      Nov 11, 2015 - Dec 18, 2015 Brain Program
                                                                                                                      General, Cancer The Focused ultrasound mediated immune responses in metastatic melanoma
                                                                                                                        Nov 01, 2015 - Nov 01, 2017 Brain Program
                                                                                                                        Brain, General Neuronavigation-guided and Ultrasound-Monitored Human BBB-opening Focused...
                                                                                                                          Nov 01, 2015 - Oct 31, 2016 Brain Program
                                                                                                                          Brain, General Transcranial Histotripsy for Treatment of Brain Tumors
                                                                                                                            Oct 21, 2015 - Feb 21, 2016 Brain Program
                                                                                                                            Brain, General Method for fully 3D volumetric thermometry, with application to transcranial...
                                                                                                                              Oct 09, 2015 - Oct 08, 2016 Brain Program
                                                                                                                              Bone, Non-metastases Pediatric Focused Ultrasound Computational Data Center and Registry
                                                                                                                                Oct 01, 2015 - Dec 31, 2017 Research Award
                                                                                                                                Back & neck pain Low Intensity Pulsed Ultrasound (LIPUS) for the Treatment of Spinal Disc...
                                                                                                                                  Oct 01, 2015 - Sep 30, 2016 Research Award
                                                                                                                                  Brain, General Thermal Dose Experiment in a Pig Model
                                                                                                                                    Jul 24, 2015 - Feb 19, 2016 Brain Program
                                                                                                                                    Atrial Fibrillation Trans-Esophageal Cardiac Ablation Using High Intensity Focused Ultrasound: A...
                                                                                                                                      Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                                                      Movement Disorders, General Modulated focused ultrasound for treatment of de-myelinating axons in multiple...
                                                                                                                                        Jun 01, 2015 - Nov 30, 2016 Research Award
                                                                                                                                        Back & neck pain Treatment of facetogenic lumbar back pain
                                                                                                                                          Mar 02, 2015 - Mar 01, 2016 Research Award
                                                                                                                                          General, Cancer Sonodynamic therapy for treatment of C6 glioma in a rat model – Step 2: P...
                                                                                                                                            Feb 12, 2015 - Feb 11, 2016 Brain Program
                                                                                                                                            Brain, General Enhancement of FUS Mediated Delivery of Stem Cells to Brain
                                                                                                                                              Feb 01, 2015 - Jan 31, 2016 Research Award
                                                                                                                                              Parkinson’s Disease Focused Ultrasound for Increased Delivery of Intranasal DNA Nanoparticles to...
                                                                                                                                                Feb 01, 2015 - Jan 31, 2017 Research Award
                                                                                                                                                Brain tumors, General MR-Guided Ultrasound Neurosurgery for the Treatment of Brain Tumors
                                                                                                                                                  Nov 10, 2014 - Nov 09, 2016 Brain Program
                                                                                                                                                  Psychiatric disorders A feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate...
                                                                                                                                                    Oct 13, 2014 - Oct 12, 2015 Brain Program
                                                                                                                                                    Bone, Non-metastases Magnetic Resonance-Guided High Intensity Focused Ultrasound for Pain Management...
                                                                                                                                                      Sep 12, 2014 - Sep 11, 2015 Research Award
                                                                                                                                                      Microbubble cloud formation from ultrasound contrast agents during histotripsy...
                                                                                                                                                        Aug 01, 2014 - Nov 30, 2015 Research Award
                                                                                                                                                        Brain, General Non-Invasive Treatment of Pediatric Neurological Disorders using MR-guided...
                                                                                                                                                          Jul 01, 2014 - Jun 30, 2015 Research Award
                                                                                                                                                          General, Cancer Sonodynamic therapy for treatment of C6 glioma in a rat model – Step 1: F...
                                                                                                                                                            Jun 03, 2014 - Sep 03, 2014 Brain Program
                                                                                                                                                            General, Cancer Feasibility of MR guided Lung Cancer ablation using saline flooded lung
                                                                                                                                                              Jun 01, 2014 - Aug 31, 2015 Research Award
                                                                                                                                                              Uterine fibroids Accelerated focused ultrasound ablation of uterine fibroids with MR guided...
                                                                                                                                                                  Jun 01, 2014 - May 31, 2016 Research Award
                                                                                                                                                                  Brain, General MR Temperature Imaging Toolbox for Focused Ultrasound Neurosurgery
                                                                                                                                                                    Jun 01, 2014 - May 31, 2016 Research Award
                                                                                                                                                                    General, Technology Image-guided Non-invasive Ultrasonic Thrombolysis Using Histotripsy
                                                                                                                                                                      Dec 09, 2013 - Mar 31, 2015 Research Award
                                                                                                                                                                      Head and neck cancer Magnetic Resonance Guided High Intensity Focused Ultrasound for Head and Neck...
                                                                                                                                                                        Dec 01, 2013 - Jun 01, 2016 Research Award
                                                                                                                                                                        General, Cancer Deep Penetrating Triggered Release Nanoparticles As Tumor Radiosensitizers
                                                                                                                                                                          Dec 01, 2013 - Nov 30, 2014 Research Award
                                                                                                                                                                          Brain tumors, Metastasis A Feasibility Study to Evaluate the Safety and Feasibility of Transcranial...
                                                                                                                                                                              Jul 12, 2013 - Nov 01, 2015 Brain Program
                                                                                                                                                                              General, Technology Nanoagents for improving focused ultrasound thermal delivery to tumors with...
                                                                                                                                                                                Jul 01, 2013 - Dec 15, 2014 Research Award
                                                                                                                                                                                Prostate The Effect of Focused Ultrasound Ablation on Adjacent Nerve Function
                                                                                                                                                                                  Jun 30, 2013 - May 31, 2018 Research Award
                                                                                                                                                                                  General, Technology Real-time 3D MR Thermometry for Focused Ultrasound Surgery
                                                                                                                                                                                    Jun 10, 2013 - Jun 09, 2014 Research Award
                                                                                                                                                                                    Osteoarthritis Pain Alleviation of Magnetic Resonance-guided Focused Ultrasound Surgery...
                                                                                                                                                                                      Jun 10, 2013 - Jun 01, 2016 Research Award
                                                                                                                                                                                      FUS-mediated Functional Neuromodulation for Neurophysiologic Assessment in a...
                                                                                                                                                                                        Jun 01, 2013 - May 31, 2014 Research Award
                                                                                                                                                                                        Epilepsy Target-Specific FUS Treatment Envelope Survey in Cadaveric and Ex-Vivo...
                                                                                                                                                                                          Mar 26, 2013 - Jun 25, 2013 Brain Program
                                                                                                                                                                                          Prostate MR Directed Focal Hyperthermia for Pelvic Disease
                                                                                                                                                                                            Dec 01, 2012 - Dec 10, 2014 Research Award
                                                                                                                                                                                            A New Application for MR-guided Focused Ultrasound: Amplification and...
                                                                                                                                                                                              Nov 01, 2012 - Oct 31, 2014 Research Award
                                                                                                                                                                                              Brain, General In vivo transcranial cavitation study of low-frequency focused ultrasound in...
                                                                                                                                                                                                Sep 17, 2012 - Sep 16, 2013 Brain Program
                                                                                                                                                                                                Parkinson’s Disease A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate...
                                                                                                                                                                                                    Sep 12, 2012 - Dec 12, 2013 Brain Program
                                                                                                                                                                                                    Brain, General Phase Aberration Correction for Transcranial MRgFUS using a Hybrid Simulation...
                                                                                                                                                                                                      Aug 17, 2012 - Aug 16, 2013 Brain Program
                                                                                                                                                                                                      Alzheimer’s Disease Blood-brain barrier opening for facilitating drug delivery in neurological and...
                                                                                                                                                                                                        Aug 01, 2012 - Jul 31, 2013 Research Award
                                                                                                                                                                                                        Pancreatic tumors MR-guided HIFU enhanced targeted drug delivery for treatment of pancreas...
                                                                                                                                                                                                          Mar 09, 2012 Liver/Pancreas Program
                                                                                                                                                                                                          Brain tumors, General Targeted Delivery of Controlled Release Nanoparticles to Brain Tumors Using...
                                                                                                                                                                                                            Jan 01, 2012 - Dec 31, 2017 Research Award
                                                                                                                                                                                                            Uterine fibroids Updated Costs of Uterine Fibroid Treatments Including Focused Ultrasound Surgery
                                                                                                                                                                                                              Nov 15, 2011 - Nov 14, 2012 Research Award
                                                                                                                                                                                                              Brain tumors, General Tests of microbubble-enhanced ablation in a large animal model with a...
                                                                                                                                                                                                                Oct 01, 2011 - Dec 31, 2012 Research Award
                                                                                                                                                                                                                General, Cancer Hypoxia-directed Magnetic Resonance-guided Focused Ultrasound Therapy
                                                                                                                                                                                                                  Aug 01, 2011 - Jan 31, 2013 Research Award
                                                                                                                                                                                                                  Brain, General Detection and Characterization of Intracranial Cavitation Activity
                                                                                                                                                                                                                    Aug 01, 2011 - Jul 31, 2012 Brain Program
                                                                                                                                                                                                                    Brain tumors, Metastasis A Study to Evaluate the Safety and Feasibility of Transcranial MRI-Guided...
                                                                                                                                                                                                                      Jun 15, 2011 - Jun 15, 2012 Brain Program
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