Patient selection for high intensity focused ultrasound (HIFU) prostate treatment was featured as one of the opening plenary sessions for the 2016 Annual Meeting of the American Urological Association, held earlier this month in San Diego.
Approximately 2,000 attendees filled the Friday event entitled “High Intensity Focused Ultrasound – Hope or Hype?” which was moderated by Dr. Michael O. Koch.
After four expert presentations on the FDA path to approval, the Canadian experience, the European experience, and an overview of instrumentation and techniques, the session concluded with a panel discussion on patient selection for focal treatment, hemi-ablation, and whole gland ablation.
“Urologists are looking at the data and listening to the differing opinions. They are interested in studies comparing the side effects profiles of HIFU to cryotherapy, laser ablation, and radiation,” said Foundation Chief Medical Officer Tim Meakem, MD
The list below includes the title and authors for the abstracts that featured focused ultrasound studies. Search by abstract number on the AUA 2016 website to read the full text of each abstract.
MP18-01 Whole Gland Salvage High Intensity Focused Ultrasound of Prostate: Intermediate Term Results of Prospective Phase II Clinical Trial by Khurram Siddiqui*, Michele Billia, Philippe Violette, Andrew Arifin, KimChi Tran, Joseph Chin
MP18-02 Development and Internal Validation of a Multivariable Prediction Model for Biochemical Failure after Focal Salvage High Intensity Focused Ultrasound for Locally Recurrent Prostate Cancer: Presentation of a Risk Score for Individual Patient Prognosis by Max Peters*, Taimur Shah, Abi Kanthabalan, Neil McCartan, Jochem van der Voort van Zyp, Marinus Moerland, Marco van Vulpen, Richard Hindley, Mark Emberton, Hashim Ahmed
MP18-06 Salvage External Beam Radiation Therapy (EBRT) for Local Recurrence after High Intensity Focused Ultrasound (HIFU) Failure Versus Salvage HIFU for Local Recurrence after EBRT Failure: A Matched Pair Comparison by Ji-Wann Lee, Albert Gelet, Jeremy Soria, Marc Colombel, Pascal Pommier, Christelle Melodelima, Olivier Rouviere, Lionel Badet, Sebastien Crouzet*
MP18-08 Focal HIFU for Treatment of Localised Prostate Cancer: A Multi-Centre Registry Experience by Stephanie Guillaumier*, Sami Hamid, Susan Charman, Jan van der Meulen, Neil McCartan, Karishma Shah, Richard Hindley, Raj Nigam, Tim Dudderidge, N Afzal, A Cornaby, H Lewi, Raj Persad, J Virdi, Caroline Moore, Manit Arya, Mark Emberton, Hashim Uddin Ahmed
MP18-10 Oncologic Outcomes after Hemiablation Therapy for Localized Prostate Cancer by Estefania Linares Espinos*, Jose I. Perez-Reggeti, Eric Barret, Arjun Sivaraman, Rafael Sanchez-Salas, Marc Galiano, François Rozet, Dominique Prapotnich, Nathalie Cathala, Annick Mombet, Xavier Cathelineau
MP18-15 Efficacy of High Intensity Focused Ultrasound (HIFU) As a Primary Monotherapy for Low Risk Localized Prostate Cancer: Outcomes From the ENLIGHT Trial by Cary Robertson*, Anthony Sliwinski, Eric Wallen, John Ward, William Orovan, Donald Locke, E David Crawford, Paul Maroni, Robert Donnell, Ivan Grunberger, Ivan Colon, Richard Bevan-Thomas, Ravi Munver, Ihor Sawczuk, Sam Chang, Inderbir Gill
MP18-17 Comparisons of Oncological and Functional Outcomes among Radical Retropubic Prostatectomy, High Dose Rate Brachytherapy, Cryoablation, and High-intensity Focused Ultrasound for Localized Prostate Cancer: A Prospective, Controlled, Nonrandomized Trial by Po Hui Chiang*, Yi Yang Liu
MP18-19 Local Radical Tumor Ablation through Combined Transurethral Resection and Transrectal High Intensity Focused Ultrasound: A valid therapy to treat High Risk Prostate Cancer? by Christian Chaussy*, Stefan Thueroff
MP34-16 Evaluation of a Laparoscopic High Intensity Focused Ultrasound Probe for the Ablation of Small Renal Masses by Steven V Kheyfets*, Clint D Bahler, Chandru P Sundaram
MP54-13 Detection and Assessment of Hemorrhagic Kidney Injury Caused by Burst Wave Lithotripsy using Ultrasound and Magnetic Resonance Imaging by Adam Maxwell*, Wayne Kreider, Yak-Nam Wang, Philip May, Donghoon Lee, Joshua Park, Bryan Cunitz, Mathew Sorensen, Rajash Handa, Michael Bailey, Jonathan Harper
PD06-10 Multi-parametric Magnetic Resonance Imaging to Evaluate and Monitor Prostate Cancer after High-Intensity Focused Ultrasound: Implication for Targeted Focal Therapy by Sunao Shoji*, Taro Higure, Masayoshi Kawakami, Mayura Nakano, Toshiro Terachi, Toyoaki Uchida
PD19-11 Pilot Assessment of Transcutaneous Boiling Histotripsy Ablation of the Kidney in the Porcine Model by George R. Schade*, Tatiana D. Khokhlova, Yak-Nam Wang, Frank Starr, Adam D. Maxwell, Wayne Kreider, Michael R. Bailey, Vera Khokhlova
S&T 1150 Hemiablation HIFU for Unilateral Localized Prostate Cancer: A Prospective Multicenter Trial by Pascal Rischmann*, Albert Gelet, Arnauld Villers, Gilles Pasticier, Olivier Rouvière
V5-06 Initial Experience during Development of Laparoscopic 12mm HIFU Probe by Tim Large*, Chandru Sundaram
* = Presenter
Posted May 2016